Journal article

The Impact of Out-of-Hours Presentation on Clinical Outcomes in ST-Elevation Myocardial Infarction

S Biswas, A Brennan, SJ Duffy, N Andrianopoulos, W Chan, A Walton, S Noaman, JA Shaw, A Ajani, DJ Clark, M Freeman, C Hiew, E Oqueli, J Lefkovits, CM Reid, D Stub

Heart Lung and Circulation | ELSEVIER SCIENCE INC | Published : 2020

Abstract

Background: Systems of care have been established to ensure patients with ST-elevation myocardial infarction (STEMI) get timely access to primary percutaneous coronary intervention (PPCI). In this study, we evaluated whether patients undergoing PPCI both in-hours and out-of-hours experience similar care and clinical outcomes. Methods: Of 9,865 patients who underwent PCI for STEMI from 2005 to 2016 and were enrolled in the multi-centre Melbourne Interventional Group registry, patients who had initially presented to a non-PCI capable hospital, received thrombolysis or presented >12 hours post-symptom onset were excluded. Our final study cohort of 4,590 patients were dichotomised by whether PPC..

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University of Melbourne Researchers

Grants

Awarded by Pfizer


Funding Acknowledgements

We would like to acknowledge the following sources of scholarship/grant support: The National Heart Foundation of Australia (Dr Biswas: reference no. 101518; Dr Stub: reference no. 101908), the National Health and Medical Research Council of Australia (Professor Duffy: reference no. 1111170, Dr Chan: reference no. 1052960, Professor Reid: reference no. 1045862), the Australian Government Research Training Program (Dr Biswas) and the Viertel Foundation (Dr Stub). The Melbourne Interventional Group acknowledges funding from Abbott, Astra-Zeneca, Medtronic, MSD, Pfizer, Servier and The Medicines Company. These companies do not have access to data and do not have the right to review manuscripts or abstracts before publication.